Chlorpromazine, colza pine, and lox
pine are the majority likely agents to create seizures. Most other narcoleptics,
though, are unusually connected with seizures, even after overdose. The instrument
by which narcoleptics create seizures is not well understood but probable
involves dose-related blockade of nor epinephrine reuptake and antagonism of
gamma-amino butyric acid a receptors. Narcoleptic agents have a comparatively
flat dose-response bend. Effectual therapeutic doses vary over a wide variety.
The most favorable dose is determined by the scientific retort, not by serum
drug levels. Pharmacologic belongings usually last 24 hours or more, allowing
for once-daily dosing.
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